It’s the epitome of DTLA cool, fusing Hollywood glamour in the old HQ of the Los Angeles Railway with contemporary style – all at fairly approachable prices. You’ll no doubt want to spend a chunk of time catching rays by the rooftop pool, but peel yourself up from the comfy loungers and you’ll be rewarded with social brunches in the foliage-filled Sibling Rival bistro. When it’s time to hit the sheets, you’ll find rooms with House of Hackney prints, nodding back to the London brand's roots.

Calling all shopaholics: DTLA’s most popular fashion hotspot is only a five-minute walk from the Hoxton. Every day of the year, rain or shine, bargain-hunters descend on this market-style strip to stock up on flashy jewelry, men’s suits, lush fabrics or children’s toys. It can be a bit of a scrum, so come armed with patience and a readiness to haggle – and remember that everything is final sale. Bring an energy for people-watching, too: the unofficial second sport of a visit to this strip.

In this historic quarter of LA, a lot of the most exciting must-sees have been born from crumbling old buildings – and City Market South is a perfect example. Once home to LA’s oldest produce market, the brick-fronted hall, a 10-minute walk from the Hoxton, was revamped under a decade ago into a dining and shopping hub, stuffed with trendy eats such as Superfine Pizza and Cognoscenti Coffee. After you’ve had your fill of grazing, sink a couple of cocktails at Dama. Make ours a margarita...

For more than a century, it’s been supplying bountiful blooms to the city and its surrounds – so, the Los Angeles Flower Market, a 15-minute walk from the Hoxton, is a colorful stop on your neighborhood tour. It’s technically a wholesale market, so you might not be in the, er, market to purchase – unless you’re in town to supply a wedding. But you can still pop in for a morning browse, any time from when doors open at the crack of dawn. Remember, cool morning climes = fresh, perky flowers.

Don’t let the name confuse you: this isn’t a Mickey Mouse-style themed attraction, but rather a grand, landmark performance venue, home to the Los Angeles Philharmonic. The eye-catching Frank Gehry-designed exterior is enough to justify a visit – a vision in geometric steel, it’s a distinct contrast to the crumbling old-school architecture that fills much of Downtown. A quick five-minute cab ride from the Hoxton brings you in for a concert. Whatever you book will be a musical feast.

When it’s time for a nightcap – or, for that matter, a sundowner – whiskey lovers need look no further than Seven Grand, a 15-minute walk (or stumble) from your room at the Hoxton. Live music, pool tables and elegantly dressed bar staff will welcome you as you step into the low-lit space, home to the best collection of international whiskies in Downtown LA. A connoisseur? Make for Bar Jackalope, tucked behind Seven Grand, for 120 varieties, including rare Japanese, Scotch and Irish bottlings.

After a night on the (down)town, there’s nothing that blows hangovers away quite like a plate of fried chicken. The trendy set make for Poppy + Rose, a stylish comfort-food haunt with dishes both healthy (avo toast) and not (pork hash or the aforementioned buttermilk-fried chicken and waffles). Do book ahead; it’s been named the best breakfast in the city more than once, and if you leave it late you might be denied a sought-after seat.

The Grammys, the music world’s biggest awards ceremony, epitomize LA glamour. Just a 10-minute walk from the Hoxton you can take a deep-dive into their intricacies at this themed museum, boasting exhibits on acclaimed bands, as well as regularly scheduled expert discussions. There are live performances, too: keep an eye to see who’s slated to perform next, so you can book tickets as soon as they’re released.