At the foot of the South Mountain Preserve, Arizona Grand Resort & Spa offers front-row access to Phoenix’s natural wonders, from the rugged mountains to majestic saguaros. Unwind in your luxury suite or residential-style villa with spectacular views of the pond and golf course. Spend the day at the seven-acre Oasis waterpark, floating on the lazy river, swimming in the wave pool, or soaking up the sun in a private cabana.

You’ll feel calm and collected after your stay at Sanctuary in Scottsdale. Located near the stunning Camelback Mountain, this 53-acre resort brings the beauty of the desert to you. Find your zen in the meditation garden, be still by the serene reflection pond or spend a day at the spa for unique services like the Golden Lotus Balancing Ritual, where healing herbs are wrapped around your body like a cocoon. Don’t miss a sunrise yoga class with views of the Red Rock Mountains and flowering cacti.

Prepare for the celebrity treatment at Canyon Ranch, an iconic gem in Arizona’s Sonoran Desert. The all-inclusive resort boasts over 300 services to curate your stay, from spa renewal packages and nutrition classes to daily wellness activities like hypnotherapy and crystal sound activation. Take a guided hike or bike ride on the desert trails. Visit the ancient sites of the Hohokam people around the Tuscon Valley. Or, become one with your thoughts via meditation journaling classes.

As the name suggests, Hilton Sedona Resort is just a stone’s throw from Bell Rock—one of the world’s most famous vortex sites. Harnessing the area’s magnetic energy, the property’s expansive spa offers a variety of signature treatments and energy-based therapies designed to balance and nourish the mind, body, and soul. Spend a morning with a tarot card reading followed by sound bowl therapy and chakra stone balancing. Stargaze from your private balcony with clear views of the Sedona night sky.

Imagine soaking in a natural hot spring surrounded by the beauty of the Bradshaw Mountains – at Castle Hot Springs, you can. Known for being Arizona’s first wellness resort, this off-the-beaten-path oasis is home to a three-acre farm (the source of the resort’s farm-to-table dining), mineral-rich geothermal hot springs, a spa, and a wealth of adventures and activities. Take a spin on a cruiser bike to explore the property’s expansive grounds.

Drawing inspiration from the surrounding Sonoran Desert, Miraval Arizona Resort & Spa offers an experimental and immersive approach to wellness. For one, you’ll have to ditch your phones, tablets and computers – this spa is all about being technology-free to promote mindfulness and wellness. Here, it’s all about becoming one with nature. Listen to a coyote’s howl. Watch a hummingbird flutter around the colorful cacti. Take a dip in a pool that connects directly to the desert.

Escape the stress of everyday life and find peace among Sedona’s red rocks and ponderosa pine groves at Enchantment Resort. Hidden in the breathtaking Boynton Canyon, this secluded spa retreat is a place to find balance and recharge. Stay in a stunning Southwestern-inspired casita with a private deck overlooking the unique rock formations. Dine on locally sourced meals at Che Ah Chi featuring dishes like wild mushroom risotto or duck breast with broiled cauliflower.

Located just outside Scottsdale, CIVANA Wellness Resort and Spa is a playground of well-being and home to not only fitness experiences (aerial yoga, anyone?) but also healing treatments, outdoor adventures, and mouthwatering dining. Get lost in the Sonoran desert on a guided hike or biking experience on the Tortuga Trail. Enjoy a specialized treatment like the Sonoran Rain Dance – a water therapy designed to enhance relaxation and restore homeostasis.