For epic shopping and delicious eats, you’d be hard-pressed to find a better spot for your girls’ weekend getaway than the Windy City. Shop ‘til you drop at the vintage shops of Chicago neighborhoods like Bucktown and Wicker Park, like Penelope’s and Una Mae’s. Dive headfirst into the deep-dish pizza scene at beloved pizzerias like Pizano’s Pizza and Pequod's. For happy hour, take a Chicago River sunset cruise (or consider one aboard a floating Tiki Bar) to admire the skyscraper scenery.

If you’re a sucker for a dreamy aesthetic, then the palm-lined streets of Palm Springs are where you need to be. Between the year-round sunshine, epic Palm Canyon Drive shopping, and Wes Anderson–esque hotels, it’s no surprise this desert gem is one of the top US travel spots for women. Start with cocktails at the ultra-stylish Pink Cabana or bottomless mimosas at Pinocchio’s. Explore the famous Palm Springs Walk Of Stars and historic districts, where legends like Marilyn Monroe once lived.

From the pastel-hued buildings of Rainbow Row to the nightlife spots of King Street, Charleston offers the perfect blend of feminine energy and Southern charm. Hit the streets in a horse-drawn carriage, indulge your dark side with a historical ghost tour, and don’t miss an opportunity to catch the Lowcountry sunset from the water. Dine al fresco at Park & Grove (the avocado toast is a must), chow down on your favorite seafood dishes at The Darling Oyster Bar, or consider a Charleston food tour.

If it’s high vibes and seaside glam you’re after, nowhere does it better than Miami. For MTV-worthy pool parties, check out Hyde Beach or Arcadia Day Club. Explore the lively Cuban district of Little Havana and manifest your future while sailing past the million-dollar homes of Hibiscus Island. Pose for photos with iconic street art in Wynwood, soak up the sun in South Beach, and peruse the high-end boutiques of Brickell.

Sin City, where the party never stops and you can’t throw a pebble without hitting a casino, is undoubtedly one of the best weekend retreats for a wild girls’ trip. Kick off the shenanigans with a booze-fueled Las Vegas pool party and wander the Las Vegas Strip. When you want a break from the high-octane nightlife scene, embrace your inner adrenaline seeker on a desert ATV tour, strut your stuff in an amateur photoshoot at the Neon Museum, or catch a Cirque du Soleil show at the Bellagio.

Country lovers unite in Nashville. For brunch, head to White Limozeen or Hampton Social where the vibes radiate girls’ trip energy. Pair your cocktails with show-stopping city views from Thistle & Rye or Proof. Explore music history with a backstage tour of the Grand Ole Opry or visit the Country Music Hall of Fame & Museum, then enjoy a show at The Electric Jane or the legendary Bluebird Café. On Broadway, stop at the electrifying Honky Tonk Highway for live music and nonstop partying.

If you’re hunting for weekend getaway recommendations that include tasty cuisine, awesome live music, outdoor adventures, and unbeatable nightlife, Austin is the city for you. Stroll down South Congress Avenue (SoCo) to experience Austin’s signature “weirdness” in the form of funky vintage shops, retro-modern eateries, and speakeasy bars like Midnight Cowboy. For upscale lounges and honky tonks alike, head to Fifth Street. Alternatively, visit Lady Bird Lake for a kayak tour or boat cruise.

From renowned Cajun cuisine and voodoo tours to art museums (don’t miss NOMA!) and live music, there’s far more to the Big Easy than Mardi Gras. Unwind with a picnic in Jackson Square or tackle the city’s dining scene with po’ boys at Domilise's, soul food at Queen Trini Lisa, or beignets at Café Du Monde. Of course, no trip to New Orleans would be complete without shopping on Magazine Street or bar hopping on Bourbon Street.

With its legendary landmarks, vibrant nightlife scene, and manicured parks adorned with Spanish moss, Savannah is often one of the first cities that comes to mind when we think of girls’ trip ideas. Start with a leisurely walk through Forsyth Park, an iconic green space that’s been featured in movies like Forrest Gump and Lady and the Tramp. For waterfront dining and nightlife, venture to River Street hotspots like Vic’s on the River, Electric Moon, and Rocks on the Roof.